Oh, goodness, no!
The "mastery" of a skill cannot happen until your character is level 75, minimum. You get new skills at levels 2,3,5,8,12,18,25,35,50 and 65, so you will have all your skills picked before you get any mastered. usually
The notes regarding mastery is a "guide" where to spend your alloted skill points. Highest priority to MS Lore, next highest MS Focus, etc. Once you get into the flow of the game, you will understand what this means!
Thanks for the help!